In 2016, she had a supporting role in the Nicholas Sparks romantic drama film The Choice, directed by Ross Katz. Daddario subsequently starred as one of the leads in the film adaptation of Baywatch (2017), reuniting with her San Andreas co-star Dwayne Johnson. She played Summer Quinn, who was portrayed by Nicole Eggert in the original television series. That same year, Daddario portrayed Kate Jeffries, alongside Kate Upton, in the road trip comedy The Layover (2017), directed by William H. Macy. In 2018, she appeared in the music video "Wait" by Maroon 5 and starred as Avery Martin in the romantic comedy When We First Met, opposite the film's co-writer Adam DeVine. Daddario also appeared as a Scuba Diver in Rampage directed by Brad Peyton, but was cut in the final film. Daddario is set to star as Constance Blackwood in We Have Always Lived in the Castle, a Stacie Passon-directed film adaptation of Shirley Jackson's mystery thriller novel of the same name. Daddario has been cast alongside Henry Cavill and Sir Ben Kingsley in the psychological thriller Nomis, and is also headlining the drama-thriller film Lost Girls and Love Hotels. Daddario will next be starring in and executive producing the romantic comedy film Can You Keep a Secret?, based on the novel of the same name by Sophie Kinsella.